High Quality Skin Whitening Kojic Acid CAS 501-30-4
Introduction
Kojic acid, also known as aspergillic acid and kojic acid, is a melanin-specific inhibitor. After entering skin cells, it can complex with copper ions in the cells, change the three-dimensional structure of tyrosinase, and prevent the activation of tyrosinase. , thereby inhibiting the formation of melanin. Kojic acid whitening active agents have better tyrosinase inhibitory effect than other whitening active agents. It does not act on other biological enzymes in cells and has no toxic effect on cells. At the same time, it can also enter the intercellular matrix to form intercellular colloid, which can retain water and increase skin elasticity. It has been formulated into various cosmetics to make whitening cosmetics targeting freckles, age spots, pigmentation and acne.
Application
1. Application in the field of cosmetics. In human skin, tyrosine undergoes complex oxidation and polymerization with oxygen free radicals under the catalysis of tyrosinase, and finally synthesizes melanin. Kojic acid can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of melanin in the skin. It is safe and non-toxic and will not cause white spot sequelae. Therefore, kojic acid has been formulated into lotions, facial masks, lotions, and skin creams to make It is a high-end whitening cosmetic that can effectively treat freckles, age spots, pigmentation, acne, etc. Kojic acid at a concentration of 20ug/ml can inhibit 70-80% of the activity of various tyrosinase (or polyphenol oxidase PPO). The general amount added in cosmetics is 0.5-2.0%.
2. Food processing field. Kojic acid can be used as a food additive to preserve freshness, preservatives, and antioxidants. Experiments have shown that kojic acid can inhibit the conversion of sodium nitrite in bacon into carcinogenic nitrosamines, and adding kojic acid to food will not affect the taste, aroma and texture of the food; kojic acid is also used to produce maltol and ethyl maltol. As a raw material, kojic acid has a wide range of applications in food processing.
3. Pharmaceutical field. Since kojic acid has no mutagenic effect on eukaryotic cells, and can eliminate free radicals in the human body and enhance leukocyte motility, which is beneficial to human health, kojic acid has been used as a raw material for cephalosporin antibiotics to produce finished drugs for treatment It has ideal analgesic and anti-inflammatory effects on headaches, toothaches, local inflammation and other diseases.
4. In the agricultural field. Kojic acid can be used to produce biopesticides. Bio-microfertilizer (dark red liquid) made by adding 0.5 to 1.0% kojic acid, whether it is sprayed as a foliar fertilizer at a low concentration, or made into a growth and yield increasing agent for root application, this crop production accelerator is beneficial to grain and Vegetables have obvious yield-increasing effects.
5.In other fields. Kojic acid can also be used as an iron analysis reagent, film spot remover, etc.
Certificate of Analysis
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Product Name: |
Kojic acid |
Manufacture Date: |
2023-10-28 |
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Batch No.: |
Ebos-231028 |
Test Date: |
2023-10-28 |
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Quantity: |
25kg/Drum |
Expiration Date: |
2025-10-27 |
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ITEMS |
STANDARD |
RESULTS |
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Appearance |
White or almost white crystal powder |
Conforms |
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Assay |
≥98.0% |
99.1% |
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Melting point |
92.0~96.0℃ |
94.0-95.6℃ |
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Loss on drying |
≤0.5％ |
0.10% |
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Ignition residue |
≤0.5% |
0.06 % |
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Heavy metal |
≤10ppm |
Conforms |
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Arsenic |
≤2ppm |
Conforms |
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Aerobic bacterial Count |
≤1000cfu/g |
Conforms |
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Total Yeast & Mold |
≤100cfu/g |
Conforms |
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E.Coli |
Negative |
Negative |
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Salmonella |
Negative |
Negative |
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Conclusion |
Conform to the specification of the requirement. |
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Storage |
Store in a cool and dry place, keep away from direct strong and heat. |
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Shelf Life |
Two years if sealed and store away from direct sun light. |
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Tester |
01 |
Checker |
06 |
Authorizer |
05 |
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