Cosmetic Grade Arbutin CAS NO 497-76-7 Beta-arbutin for Skin Whitening

Short Description:

Product Name:Beta-arbutin

Specifications: ≥99%

Appearance: White powder

Certificate:GMP、Halal、kosher、ISO9001、ISO22000

Shelf Life:2 Year

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Introduction

Arbutin, also known as arbutin, is an ingredient extracted from bearberry leaves of the Rhododendron plant. It can prevent the production of melanin by inhibiting the activity of tyrosinase in the body, thereby reducing skin pigmentation and removing stains. and freckles. It also has bactericidal and anti-inflammatory effects and is used in cosmetics.

Arbutin is found in many plants, including some common herbs and foods. It is a flavonoid glycoside, divided into two forms: α-arbutin and β-arbutin. Although the chemical structures of the two are similar, there are differences in their pharmacological and biological activities.

Application

Arbutin is an ideal whitening agent for whitening cosmetics. It is also called hydroquinone glucoside. It has two optical isomers, namely α and ß types. The ß isomer is the most biologically active. β-Arbutin is a white slightly yellowish powder at room temperature. It is easily soluble in water, methanol, ethanol, propylene glycol, and glycerol aqueous solutions. There is no precipitation after dissolution. It is insoluble in chloroform, ether, petroleum ether, etc. It is added to many whitening skin care products.

Arbutin, also known as arbutin, refers to an active substance extracted from the leaves or fruits of bearberry. It is a white needle-shaped crystal or powder that combines "green plant, safe and reliable" and "efficient decolorization". An all-in-one skin depigmentation component, it can quickly penetrate into the skin. Without affecting the concentration of cell proliferation, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly bind to tyrosinase by itself. , accelerates the decomposition and excretion of melanin, thereby reducing skin pigmentation, removing spots and freckles, and does not produce toxic, irritating, sensitizing and other side effects on melanocytes. It also has bactericidal and anti-inflammatory effects.

Certificate of Analysis

Product Name:		Beta Arbutin	Manufacture Date:			2023-10-15
Batch No.:		Ebos-231015	Test Date:			2023-10-15
Quantity:		25kg/Drum	Expiration Date:			2025-10-14

ITEMS		STANDARD				RESULTS
Assay		≥99%				99.99% HPLC
Physical Characteristics
Appearance		White crystalline powder				Conforms
Hydroquinone		Negative				Negative
Melting Point		203-206（±1）℃				203.9-205.6 ℃
Specific Optical Rotation		[a]²⁰D= + 174.0°- +186.0°				+179.81°
Infrared peak value		1514cm^-1; 1229 cm^-1; 1215 cm^-1; 1059 cm^-1; 1034 cm^-1				1514cm^-1; 1229 cm^-1; 1215 cm^-1; 1059 cm^-1; 1034 cm^-1
Solubility		Soluble in water, slightly soluble in ethanol				Conforms
Clarity		Solution should be clarify, none suspended matters				Conforms
PH (1% water solution)		5.0-7.0				6.28
Loss on drying		≤0.5%				0.01%
Residue on Ignition		≤0.5%				0.01%
Heavy Metals
Heavy metals		≤10ppm				Conforms
Lead		≤2ppm				Conforms
Arsenic		≤2ppm				Conforms
Mercury		≤1ppm				Conforms
Microbiological Tests
Total Plate Count		≤100cfu/g				Conforms
Total Yeast & Mold		≤50cfu/g				Conforms
E.Coli		Negative				Negative
Salmonella		Negative				Negative
Conclusion		Conform to the specification of the requirement.
Storage		Store in a cool and dry place, keep away from direct strong and heat.
Shelf Life		Two years if sealed and store away from direct sun light.
Tester	01	Checker		06	Authorizer		05

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